TM-FLOW

Distributor Company: Med-Essence Kft.

Address: 1222 Budapest, Orkán u. 11.

Website: www.e-med.hu

Manufacturer Company: LD Technology

Address: 100 N. Biscayne blvd. #502

33132 Florida, Miami

TM-Flow is a Medical Device Data System with the intended use of TBL-ABI Model C001, SweatC Model A001, and LD-Oxy Model D001.

· Measurement of Ankle Brachial Indices for the screening of Peripheral Artery Disease.

· Measurement of the Galvanic Skin response related to the sudomotor function.

· Mathematical Analysis of the Photoplethysmography for assessing:

. The Autonomic nervous system via Heart Rate Variability Analysis at rest and during the Ewing Tests.

. The Endothelial function via the Photoplethysmography (PTG) Analysis.

Clinical studies compared the accuracy of the TM-Flow:

· PTG Spectral Analysis Markers to the:

- The gold standard of Insulin resistance assessment

- Hyperinsulinemic Euglycemic Clamp.

- Coronary angiography.

- Vascular blood tests ( CRP and fibrinogen)

· Cardiometabolic Score to the Oral Glucose Tolerance Test (OGTT).

· Sudomotor markers to the:

- Small fiber Neuropathy Symptoms.

- Microvascular disease (retinopathy).

TM FLOW MAIN MARKERS

Vascular Function Assessment

Arterial stiffness and Ankle Brachial Indices from the Volume plethysmography analysis
Endothelial FunctionPatented markers from mathematical analysis of the photoplethysmography spectral analysis. (Off label use)

Autonomic Nervous System Assessment

Sudomotor Function Markers.
Heart rate variability Analysis (HRV)
Cardiac Autonomic Reflex Tests
- Valsalva Ratio,
- E/I Ratio ,
- K30/15 Ratio and
- Systolic Pressure Response to Standing.